Have you heard of Goowy? If not, it's a great app, and completely lives in your web browser, but in Flash cool animated goodness. Calendar, email (from any account!), contacts, RSS feeds, widgets, and games all in a customizable interface. Oh, did I mention, of course...it's FREE?
If you're looking to break free of Outlook, and Gmail and Yahoo are too boring, let Goowy take over. I'll be using it while on the road.